Document Type : Original articles

Authors

1 Department of Pediatrics, College of Medicine, University of Anbar, Ramadi, Anbar, Iraq

2 Department of Pediatrics, Al-Ramadi Maternity and Children Teaching Hospital, Ramadi, Anbar, Iraq

Abstract

Background: Congenital heart disease (CHD) carries a high rate of mortality and morbidity in the pediatric population. The gold standard technique for diagnosing CHD is echocardiographic examination.
Objectives: to assess the CHD pattern among children referred for echocardiography in Ramadi city, west of Iraq and to determine the correlation of various types of CHD with age and gender.
Materials and Methods: The study conducted at Maternity and Children Teaching Hospital in Ramadi. All patients who evaluated by echocardiography from June 2013 to March 2015 were included in this study. All children were evaluated by transthoracic echocardiography using M-mode by a pediatrician trained in pediatric ECHO. The pattern of CHD was studied, taking into consideration age and gender distribution.
Results: the age range of our 262 patients was 1 day to 14 years (mean 16.6±30.3 months) and the male to female ratio 1.04:1. Acyanotic CHD comprises 87% of the cases.  There were 188 (71.76%) patients diagnosed in infancy. Ventricular septal defects (29.39%) were the commonest type, atrial septal defects (16.03%) were the second, and the least Ebstein anomaly (0.38 %). The commonest cyanotic cardiac defect was Fallot Tetralogy. There was a male predominance in ventricular septal defects, Tetralogy of Fallot, aortic stenosis, coarctation of the aorta, and D-transposition of the great arteries. While,  female predominance observed in atrioventricular canal defect, atrial septal defects, patent ductus arteriosus, and pulmonary stenosis.
Conclusion: CHD mostly diagnosed in the infants. Acyanotic CHD was the commonest defect. Ventricular septal defects were the commonest acyanotic defect. While Fallot Tetralogy was the commonest cyanotic CHD. Sex distribution was comparable to that observed in the studies from other parts of the world.

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[1]      H. Dolk, M. Loane, E. Garne, and  a E. S. of C. A. (EUROCAT) W. Group, “Congenital heart defects in Europe: prevalence and perinatal mortality, 2000 to 2005,” Circulation, vol. 123, no. 8, pp. 841–849, 2011.
[2]      W. Rosamond, “American Heart Association statistics committee and stroke statistics subcommittee. Heart disease and stroke statistics-2007 update: a report from the American Heart Association statistics committee and stroke statistics subcommittee,” Circulation, vol. 115, pp. e69–e171, 2007.
[3]      D. van der Linde et al., “Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis,” J. Am. Coll. Cardiol., vol. 58, no. 21, pp. 2241–2247, 2011.
[4]      O. Romano‐Zelekha, R. Hirsh, L. Blieden, M. S. Green, and T. Shohat, “The risk for congenital heart defects in offspring of individuals with congenital heart defects,” Clin. Genet., vol. 59, no. 5, pp. 325–329, 2001.
[5]      J. Burn et al., “Recurrence risks in offspring of adults with major heart defects: results from first cohort of British collaborative study,” Lancet, vol. 351, no. 9099, pp. 311–316, 1998.
[6]      H. K. Gill, M. Splitt, G. K. Sharland, and J. M. Simpson, “Patterns of recurrence of congenital heart disease: an analysis of 6,640 consecutive pregnancies evaluated by detailed fetal echocardiography,” J. Am. Coll. Cardiol., vol. 42, no. 5, pp. 923–929, 2003.
[7]      I. B. Vijayalakshmi, P. S. Rao, and R. Chugh, A comprehensive approach to congenital heart diseases. JP Medical Ltd, 2013.
[8]      M. Abdulkadir and Z. Abdulkadir, “A systematic review of trends and patterns of congenital heart disease in children in Nigeria from 1964-2015,” Afr. Health Sci., vol. 16, no. 2, pp. 367–377, 2016.
[9]      J. Popelova, E. Oechslin, H. Kaemmerer, and M. G. S. J. Sutton, Congenital heart disease in adults. CRC Press, 2008.
[10]    N. McIntosh and B. Stenson, “The newborn,” Forfar Arneil’s Textb. Pediatr. Newyork Churchill Livingstone, pp. 177–392, 2008.
[11]    W. W. Lai et al., “Guidelines and standards for performance of a pediatric echocardiogram: a report from the Task Force of the Pediatric Council of the American Society of Echocardiography,” J. Am. Soc. Echocardiogr., vol. 19, no. 12, pp. 1413–1430, 2006.
[12]    M. D. Cheitlin et al., “ACC/AHA/ASE 2003 guideline update for the clinical application of echocardiography: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASE Committee to Update the 1997 Guid,” J. Am. Coll. Cardiol., vol. 42, no. 5, pp. 954–970, 2003.
[13]    R. Jonas, Comprehensive surgical management of congenital heart disease. CRC press, 2002.
[14]    Y. MEMON, R. MAJEED, and F. MEMON, “Pattern of congenital heart disease at Liaquat University Hospital Hyderabad,” Pakistan Hear. J., vol. 40, no. 1–2, 2012.
[15]    S. A. Salem and O. A. El-Feky, “Epidemiological study of congenital heart diseases among children attending outpatient clinics of Benha University Hospital,” Egypt J Community Med, vol. 28, pp. 69–87, 2011.
[16]    D. F. Dickinson, R. Arnold, and J. L. Wilkinson, “Congenital heart disease among 160 480 liveborn children in Liverpool 1960 to 1969. Implications for surgical treatment.,” Heart, vol. 46, no. 1, pp. 55–62, 1981.
[17]    J. Khadim and S. Issa, “SPECTRUM OF CONGENITAL HEART DISEASES IN BASRA: AN ECHOCARDIOGRPHY STUDY,” Med. J. Basrah Univ., vol. 27, no. 1, pp. 15–18, 2009.
[18]    H. K. Saleh, “Pattern of congenital heart disease in Southern Yemeni children referred for echocardiography.,” Saudi Med. J., vol. 30, no. 6, pp. 824–828, 2009.
[19]    A. Robida, G. M. Folger, and H. A. Hajar, “Incidence of congenital heart disease in Qatari children,” Int. J. Cardiol., vol. 60, no. 1, pp. 19–22, 1997.
[20]    S. M. Al-Hamash, “Pattern of Congenital Heart Disease A Hospital-Based Study,” Al-Kindy Coll. Med. J., vol. 3, no. 1, pp. 44–48, 2006.
[21]    S. Abqari, A. Gupta, T. Shahab, M. U. Rabbani, S. M. Ali, and U. Firdaus, “Profile and risk factors for congenital heart defects: A study in a tertiary care hospital,” Ann. Pediatr. Cardiol., vol. 9, no. 3, p. 216, 2016.
[22]    K. Amro, “Pattern of congenital heart disease in Jordan,” Eur J Gen Med, vol. 6, no. 3, pp. 161–165, 2009.
[23]    B. S. Mustafa, “Pattern of congenital heart disease at Ibn-Seena Teaching Hospital-Mosul/Iraq,” Med. J. Tikrit, vol. 18, no. 182, pp. 115–120, 2012.
[24]    M. Borzouee and M. Jannati, “Distribution and characteristics of the heart disease in pediatric age group in southern Iran,” Chest, vol. 167, pp. 2–9, 2008.
[25]    A. Joundishapour, “Prevalence of congenital heart disease in iran: a clinical study,” J. Med. Sci, vol. 8, no. 6, pp. 547–552, 2008.
[26]    A. A. A. Alabdulgader, “Congenital heart disease in Saudi Arabia: current epidemiology and future projections,” 2006.
[27]    O. Başpinar, S. Karaaslan, B. Oran, T. Baysal, A. M. Elmaci, and A. Yorulmaz, “Prevalence and distribution of children with congenital heart diseases in the central Anatolian region, Turkey,” Turk J Pediatr, vol. 48, no. 3, pp. 237–243, 2006.
[28]    J. C. dos S. Guitti, “Epidemiological characteristics of congenital heart diseases in Londrina, Paraná South Brazil,” Arq. Bras. Cardiol., vol. 74, no. 5, pp. 400–404, 2000.
[29]    F. Liu et al., “Prevalence of congenital heart disease in Xinjiang multi-ethnic region of China,” PLoS One, vol. 10, no. 8, p. e0133961, 2015.
[30]    M. D. Reller, M. J. Strickland, T. Riehle-Colarusso, W. T. Mahle, and A. Correa, “Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005,” J. Pediatr., vol. 153, no. 6, pp. 807–813, 2008.
[31]    R. V Nair, V. Nair, R. V Mookambika, R. G. M. Rao, and S. N. Somayaji, “A case of single ventricular heart, pulmonary atresia, patent ductus arteriosus, major aortopulmonary collateral arteries,” Asian J. Med. Sci., vol. 6, no. 4, pp. 96–98, 2015.
[32]    H. D. Allen, D. J. Driscoll, R. E. Shaddy, and T. F. Feltes, Moss & Adams’ heart disease in infants, children, and adolescents: including the fetus and young adult. Lippincott Williams & Wilkins, 2013.